FROM BENIGN POLYCLONAL TO MALIGNANT MONOCLONAL LYMPHOPROLIFERATION IN A PATIENT WITH PRIMARY SJÖGREN'S SYNDROME
نویسندگان
چکیده
منابع مشابه
Role of B cells in Sjögren's syndrome--from benign lymphoproliferation to overt malignancy.
The classical view of B cell biology is that these cells respond to foreign and self antigens and in this way promote protection, primarily by production of antibodies. However, recent studies suggest that B cells have diverse functions within the immune system other than antibody production, which could contribute to autoimmunity. This involves organization of lymphoid tissue, regulation of de...
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Primary non-Hodgkin lymphoma of liver is a very rare malignancy. Here we report a case of primary hepatic Burkitt’s lymphoma in a 34-year old man who was known case of acquired immunodeficiency syndrome (AIDS) and presented with weight loss, abdominal pain, and fever. Positive laboratory findings were mild anemia and elevated levels of lactate dehydrogenase (LDH) and alkaline phosphatase (AL...
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概要 軽微な単 クローン性免疫 グロブ リン血症(MG)を 認めて,7年 後に骨髄腫 と診断 された症例 を経験 した.骨 髄腫の 自然史をほぼ完全に近 く把握 し得た例の詳細な報告はきわ めて乏 しいので報告 した.症 例.1910年 生,男 性 。1967年 血清肝炎.(脊 椎辻 り症の手術)に 罹患 した際,偶 然に少量のM 成分が証明 された.そ の後,M成 分は漸増 したが,骨 髄腫にかん しては無症状 に経過 した.1972年9 月,肝 硬変症,糖 尿病,MGで 入院. M成 分(IgG-K型)3.og%,骨 髄 中形質 細胞 の増 多(10~17.6 %)と 軽度ない し中等度の形態異常,正 常Igの 減少を認めたが,骨X線 像で定型的骨破壊像 を欠 き, potentially malignant typeと して追跡 した.約1年 後に,激 しい腰 痛を訴え,骨 髄...
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Background: The unique expression of fibromodulin (FMOD) in patients with chronic lymphocytic leukemia (CLL) has been previously reported. Detecting FMOD in CLL patients using specific anti-FMOD mAbs might provide a promising method in detection, monitoring, and prognosis of CLL. Objectives: In this study, we aimed for producing specific antibodies agains...
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Metastatic survey of the patients with known primary malignancies with bone scan is one of the most common studies in nuclear medicine. Unfortunately the conventional planar bone scan has a very low specificity for differentiating benign from malignant lesions especially in the spinal column. In this study, we compared the specificity of SPECT imaging and convention...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1981
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780240613